Severe hemorrhagic cystitis often arises from anticancer chemotherapy or radiotherapy for pelvic malignancies. Infectious etiologies are less common causes except in immunocompromised hosts. These cases can be challenging problems for the urologist and a source of substantial morbidity and sometimes mortality for the patients. A variety of modalities of treatment have been described for the management of hemorrhagic cystitis but there is none that is uniformly effective. Some progress has been made in the understanding and management of viral hemorrhagic cystitis. This article reviews the common causes of severe hemorrhagic cystitis and the currently available management options.
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Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. DOI: Babbitt and William R. Drobyski and Robert C. Ash and Donald R. Carrigan and Gerald V. Adenovirus infections in bone marrow transplant BMT recipients over 4 years were retrospectively reviewed. Forty-two patients There was a higher incidence of adenovirus infections in pediatric patients than in adults View on PubMed. Save to Library. Create Alert. Launch Research Feed.
Share This Paper. Topics from this paper. Adenovirus Infections Adenoviruses. Acute GVH disease Transplanted tissue. Transplant Recipients. Citations Publications citing this paper. Adenoviruses in immunocompromised hosts. Adenovirus infections in adult recipients of blood and marrow transplants.
Adenovirus infection in paediatric allogeneic stem cell transplantation recipients is a major independent factor for significantly increasing the risk of treatment related mortality. Cairo Medicine British journal of haematology Adenovirus infection after pediatric bone marrow transplantation G Hale , H.
Adenovirus infections in hematopoietic stem cell transplant recipients. Dianna S. Adenovirus infections following allogeneic stem cell transplantation: incidence and outcome in relation to graft manipulation, immunosuppression, and immune recovery. Milligan Medicine Blood Cidofovir for the treatment of adenoviral infection in pediatric hematopoietic stem cell transplant patients.
Hemorrhagic cystitis: A challenge to the urologist
Hemorrhagic cystitis or haemorrhagic cystitis is an inflammation of the bladder defined by lower urinary tract symptoms that include dysuria , hematuria , and hemorrhage. The disease can occur as a complication of cyclophosphamide , ifosfamide and radiation therapy. In addition to hemorrhagic cystitis, temporary hematuria can also be seen in bladder infection or in children as a result of viral infection. Causes of hemorrhagic cystitis include chemotherapy e. Ifosfamide is the most common cause of hemorrhagic cystitis. Radiation-induced hemorrhagic cystitis develops in similar or smaller patient numbers when compared to cyclophosphamide-induced cases.
We'd like to understand how you use our websites in order to improve them. Register your interest. Haemorrhagic cystitis is defined as acute or insidious diffuse vesicle bleeding. The potential causes of bladder haemorrhage are numerous and include chemical toxins alkylating agents such as oxazophosphorine, busulfan, thiotepa, aniline, and toluidine derivatives such as dyes, insecticides and recreational drugs , immune agents penicillins and danazol , radiation external or interstitial , viruses adenovirus type 11, BK virus and influenza A and idiopathic aetiologies amyloidosis in rheumatoid arthritis. Diagnosis and treatment of this condition is frequently complicated. Vesicle haemorrhage secondary to bacterial, fungal or parasitic infections, or cancer, will not be addressed directly in this review. As such, we focus on causes and treatment of haemorrhagic cystitis that is not associated with infections or tumours.