Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. DOI: The addition of nebulized ipratropium bromide to initial emergency department therapy improves pulmonary function, but it is unclear whether this approach results in earlier hospital discharge. The early use of bolus intravenous salbutamol has also been shown to improve outcome, including earlier discharge.

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Inhaled anticholinergics as single agent bronchodilators or in combination with beta2-agonists are one of the several medications available for the treatment of acute asthma in children. To determine the effectiveness of only inhaled anticholinergic drugs i. The latest search was performed in April We included only randomised controlled trials RCTs in which inhaled anticholinergics were given as single therapy and compared with placebo or any other drug or drug combinations for children over the age of two years with acute asthma. Six studies met the inclusion criteria but were limited by small sample sizes, various treatment regimes used and outcomes assessed. The studies were overall of unclear quality. Data could only be pooled for the outcomes of treatment failure and hospitalisation.





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